![]() ![]() Scavenger receptors are documented as pattern recognition receptors and known to act in coordination with other co-receptors such as Toll-like receptors in generating the immune responses against a repertoire of ligands such as microbial pathogens, non-self, intracellular and modified self-molecules through various diverse mechanisms like adhesion, endocytosis and phagocytosis etc. ![]() Numerous scavenger receptors have been discovered so far and are apportioned in various classes (A-L). They are functionally diverse as they are involved in various disorders and biological pathways and their major function in innate immunity and homeostasis. Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous and encompass the miscellaneous group of transmembrane proteins and soluble secretory extracellular domain.
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